Publications by authors named "F Kremer"
Molossus molossus is a widely distributed neotropical bat species in the Americas, often found in urban areas. This study evaluated climate change effects on the potential geographic distribution of M. molossus, a natural host of zoonotic pathogens such as Orthohantavirus, in the Neotropical region.
View Article and Find Full Text PDFImmune dysregulation in the brain and periphery is thought to contribute to the detrimental neurodegeneration that occurs in Parkinson's disease (PD). Identifying mechanisms to reverse this dysregulation is key to developing disease-altering therapeutics for this currently incurable disease. Here we utilized the longitudinal data from the Parkinson's Progression Marker Initiative to demonstrate that circulating lymphocytes progressively decline in PD and can be used to predict future motor symptom progression.
View Article and Find Full Text PDFArticle Synopsis
- * Traditional vaccines for these toxins face challenges in production and effectiveness, prompting interest in recombinant vaccines and the need for better understanding of lesser-studied toxins.
- * The study highlights the potential of immunoinformatics to map immunodominant regions of these toxins, guiding future research to develop more effective vaccination strategies against severe animal infections.
Article Synopsis
- * The research analyzed samples from three canine OMM cell lines and human melanoma cell lines, identifying a total of 500 mutated genes in dogs, including notable ones like EP300 and NOTCH1, with 82 mutations shared between dogs and humans.
- * These findings offer important insights for understanding the genetic landscape of OMMs and could lead to the development of new treatment options for both canine and human patients in the future.