Publications by authors named "F Koppe"

Article Synopsis
  • - The study examined the real-world effects of stereotactic body radiotherapy (SBRT) in patients with stage I non-small cell lung cancer (NSCLC), focusing on acute toxicity and 90-day mortality rates among 7,279 patients treated between 2017 and 2021.
  • - Acute toxicity occurred in 3.8% of patients, while 90-day mortality was at 1.7%, with certain factors like age, sex, and lung function impacting these outcomes.
  • - The findings suggest that SBRT has a low rate of acute toxicity and acceptable mortality, with developed prediction models aiding in identifying patients at higher risk for adverse effects.
View Article and Find Full Text PDF

Introduction: Chemoradiotherapy (CRT) is the standard of care in inoperable non-small-cell lung cancer (NSCLC) patients, favoring concurrent (cCRT) over sequential CRT (seqCRT), with adjuvant immunotherapy in responders. Elderly and frail NSCLC patients have generally been excluded from trials in the past. In elderly patients however, the higher treatment related morbidity of cCRT, may outweigh the possible lower tumor control of seqCRT.

View Article and Find Full Text PDF

Background: Decision making regarding adjuvant therapy for high-risk endometrial cancer is complex. The aim of this study was to determine patients' and clinicians' minimally desired survival benefit to choose chemoradiotherapy over radiotherapy alone. Moreover, influencing factors and importance of positive and negative treatment effects (i.

View Article and Find Full Text PDF