Publications by authors named "F Khurram"

Mindfulness training has gained increasing attention as a potential intervention to improve cardiovascular health, particularly in populations with chronic conditions, such as type 2 diabetes. Given the heightened cardiovascular risk associated with type 2 diabetes, identifying effective non-pharmacological strategies to mitigate these risks is crucial. This critical review assessed the current evidence on the impact of mindfulness training on cardiovascular health in individuals with type 2 diabetes.

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Article Synopsis
  • Eculizumab is a primary treatment for paroxysmal nocturnal hemoglobinuria (PNH), but some patients may become resistant to it, leading to a condition known as eculizumab refractory PNH.
  • The study systematically reviewed 70 relevant studies on treatments for eculizumab refractory PNH, ultimately identifying four multicenter clinical trials that focused on drugs like pegcetacoplan, danicopan, and iptacopan.
  • The findings suggest that treatment plans should be tailored to individual patient needs, and further randomized controlled trials are necessary to improve treatment guidelines for eculizumab refractory PNH.
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Objective: To evaluate ocular manifestations of reverse transcriptase (RT)-PCR-confirmed SARS-CoV-2-infected patients in a validated comparative model, and additionally to evaluate the correlation between severity of COVID-19 and ocular manifestations.

Methods And Analysis: In a prospective cross-sectional study, a total of 2400 subjects were enrolled over a period of 8 months. To eliminate bias of identical ocular symptom profile in other non-COVID-19 respiratory infections and to acquire a comparative model, 1200 COVID-19 RT-PCR-positive patients (group 1) and 1200 RT-PCR-negative patients (group 2) were included.

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Background: Changes in sleep architecture are common phenomena observed in post-traumatic patients; such altered sleeping patterns have negative implications on various phases of rehabilitation. Sleep is an essential process, without which one cannot function effectively and, hence, any aberrations in the quality of sleep in such patients need to be critically analyzed.

Objective: To probe the quality of sleep in postburn patients at one year compared with a group of adequately matched controls.

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Objective: To highlight the role of fasciocutaneous flaps in the management of leg and foot defects sustained after trauma, in rural India.

Method: This was a prospective study conducted on patients with traumatic defects of the leg and foot, admitted between May 2001 and April 2007. Selection of flaps was done on the basis of defect size, site and condition of surrounding tissue.

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