Publications by authors named "F Keita Sylla"

We report on the nonlinear temporal post-compression of 7 mJ sub-40 fs pulses from a commercial kHz Ti:sapphire laser down to a record 3.8 fs duration (sub-1.5 optical cycle) in a compact single-stage gas-filled multi-pass cell (MPC), with 60% overall compression efficiency.

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  • Whooping cough, caused by Bordetella pertussis and Bordetella parapertussis, is highly contagious and particularly dangerous for infants, with Africa having the highest incidence and mortality rates.
  • A study conducted in Abidjan from April 2019 to July 2021 involved infants with coughs and their household contacts, finding a significant number of infections among both infants and family members.
  • Results showed high circulation of pertussis in the community, emphasizing the need to address obstacles to accessing recommended booster vaccinations as suggested by the WHO.
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  • - Venous leg ulcers (VLUs) are common chronic wounds characterized by redness, swelling, and pain, and their treatment typically involves compression therapy, wound care, and limb elevation.
  • - A review of 27 human studies on acellular products for VLUs found that these products generally promoted favorable healing outcomes, with some studies indicating pain reduction for patients.
  • - Despite positive findings, the authors emphasize the need for larger randomized controlled trials to strengthen the evidence regarding the effectiveness of acellular products in VLU management.
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Multi-pass cell (MPC) compressors have proven to be the method of choice for compression of high average power long-pulse Yb lasers. Yet, generating sub-30 fs pulses at high pulse energy with compact and simple components remains a challenge. This work demonstrates an efficient and cost-effective approach for nonlinear pulse compression at high pulse energy using a hybrid air-bulk MPC.

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Respiratory syncytial virus (RSV) is a significant threat to elderly populations and repeated infections that occur throughout life are poorly protective. To assess the role of prior RSV infections as well as elderly immune senescence on vaccine efficacy, we compared immune responses after virus-like particle (VLP) immunization of elderly cotton rats and young cotton rats, both previously RSV infected, in order to mimic the human population. We show that immunization of RSV-experienced young or elderly animals resulted in the same levels of anti-pre-F IgG, anti-G IgG, neutralizing antibody titers, and protection from challenge indicating that the delivery of F and G proteins in a VLP is equally effective in activation of protective responses in both elderly and young populations.

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