Publications by authors named "F KOCH"

The development of a sensitive and specific blood test for the early detection of breast cancer is crucial to improve screening and patient outcomes. Existing methods, such as mammography, have limitations, necessitating the exploration of alternative approaches, including circulating factors. Using 598 prospectively collected blood samples, a multivariate plasma-derived lipid biomarker signature was developed that can distinguish healthy control individuals from those with breast cancer.

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In Wuerzburg, Germany, a terrorist attack and a killing rampage occurred five years apart (2016 and 2021). Following a structured evaluation of the rescue mission in 2016, a bundle of quality indicators and ten "lessons learned" were defined. Aim of the presented study was to compare the two rescue missions and to critically review the lessons learned from 2016 for their implementation and feasibility.

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The digital media landscape is rapidly shifting, and some children begin using digital media in infancy. As with book reading, young children need adult guidance to learn from digital media. Joint media engagement (JME) occurs when preschool children and their parents actively use digital media together.

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Article Synopsis
  • Serum response factor (SRF) is crucial for various cellular processes like growth and movement, and it's vital for early embryonic development, specifically for forming certain structures.
  • SRF interacts with proteins CTCF and cohesin at specific genomic regions, helping to form long-range chromatin loops and manage the insulation of topologically associating domains (TADs).
  • In embryonic stem cells, SRF works with factors like SOX2 and NANOG to create three-dimensional structures that support pluripotency, indicating it has important roles in organizing chromatin at higher levels.
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