Publications by authors named "F KAUFMANN"
Article Synopsis
- Major depressive disorder (MDD) is linked to neuroinflammatory processes involving the NLRP3 inflammasome, and a study examined the impact of the NLRP3 rs10754558 polymorphism on MDD diagnoses among young adults.
- A population-based study with 1,100 participants found no significant association between the NLRP3 genotype and MDD diagnosis, but a clinical trial showed that individuals with the GG genotype had poorer treatment outcomes compared to those with GC/CC genotypes.
- Longitudinal analyses indicated that GG individuals experienced less improvement in depressive and anxiety symptoms over time, suggesting that this genotype may affect the effectiveness of psychotherapy for MDD.
Intensity modulators are fundamental components for integrated photonics. From near-infrared (NIR) to visible spectral ranges, they find applications in optical communication and quantum technologies. In particular, they are required for the control and manipulation of atomic systems such as atomic clocks and quantum computers.
View Article and Find Full Text PDFMiniaturised optical spectrometers are attractive due to their small footprint, low weight, robustness and stability even in harsh environments such as space or industrial facilities. We report on a stationary-wave integrated Fourier-transform spectrometer featuring a measured optical bandwidth of 325 nm and a theoretical spectral resolution of 1.2 nm.
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- Major depressive disorder (MDD) affects a significant portion of the population and many do not respond to typical antidepressants, suggesting biological factors at play, particularly involving the gut-brain connection.
- Chronic stress negatively impacts the intestinal barrier in mice, affecting gene expression related to tight junctions and altering gut microbiota, with variations observed between sexes.
- This study highlights how stress influences gut health, potentially linking disruptions in the intestinal barrier to depression mechanisms, and shows parallels in blood samples from women diagnosed with MDD.
We present a graph-based model for multiple scattering of light in integrated lithium niobate on insulator (LNOI) networks, which describes an open network of single-mode integrated waveguides with tunable scattering at the network nodes. We first validate the model at small scale with experimental LNOI resonator devices and show consistent agreement between simulated and measured spectral data. Then, the model is used to demonstrate a novel platform for on-chip multiple scattering in large-scale optical networks up to few hundred nodes, with tunable scattering behaviour and tailored disorder.
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