Hypoxemia after implantation of a permanent pacemaker.

We describe a case in which the patient developed profound, intermittent hypoxemia after implantation of a permanent pacemaker and subsequently after revision of its leads. Cardiac catheterization demonstrated right-to-left shunting at the level of the atria in the presence of a patent foramen ovale that required closure, resulting in the resolution of symptoms. Our report highlights the fact that the presence of a patent foramen ovale with intermittent right-to-left shunting should be considered in a differential diagnosis of hypoxemia after implantation of heart rhythm devices.

Fatal alveolar hemorrhage and Abciximab (ReoPro) therapy for acute myocardial infarction.

We describe two cases of diffuse alveolar hemorrhage and development of ARDS in patients who underwent percutaneous transluminal coronary angioplasty (PTCA) with stenting in whom Abciximab (ReoPro) was used in combination with other agents interfering with the hemostatic mechanism. The development of pulmonary infiltrates, associated with a fall in hemoglobin after the administration of Abciximab, should strongly suggest the possibility of diffuse alveolar hemorrhage. Physicians should be aware of the possible association between the use of Abciximab and the development of alveolar hemorrhage.

Directional coronary atherectomy in women compared with men.

The influence of gender on the procedural outcome of directional coronary atherectomy (DCA) is controversial. This study of 373 consecutive patients (418 lesions) undergoing DCA demonstrates that the procedural success rate of DCA is significantly lower in women compared with men (72.7 vs.

Directional coronary atherectomy can be successfully performed in the elderly.

The influence of age on the clinical and angiographic outcome of directional coronary atherectomy is evaluated. Results demonstrate that DCA can be performed successfully in the vast majority (78.7-90%) of patients in all age groups.