RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth.

Adult skeletal muscle is a plastic tissue that can adapt its size to workload. Here, we show that RhoA within myofibers is needed for overload-induced hypertrophy by controlling satellite cell (SC) fusion to the growing myofibers without affecting protein synthesis. At the molecular level, we demonstrate that RhoA controls in a cell autonomous manner Erk1/2 activation and the expressions of extracellular matrix (ECM) regulators such as and macrophage chemo-attractants such as / Their decreased expression in RhoA mutants is associated with ECM and fibrillar collagen disorganization and lower macrophage infiltration.

From macroplastics to microplastics: Role of water in the fragmentation of polyethylene.

In this work, the artificial photodegradation of polyethylene films was studied in laboratory to compare the fragmentation pathways of this polymer at air and in water. Oxidation, surface mechanical properties, crystallinity and crack propagation were monitored to investigate their influence on fragmentation. Without any external stress, fragmentation only occurred in water despite a higher level of oxidation for films weathered at air.

[Babesiasis, pediatric malaria: does confusion exist in Africa?].

The authors describe a case of febrile disease acquired by a nursling in Africa: was it induced by Pl. falciparum or by Babesia sp.? In spite of numerous microscopic and serological appraisals from veterinary and medical authorities, it is difficult to state definitively this subject, but it is more probably a babesiosis of canine or rodent origin.