Publications by authors named "F Jesseph"
Purpose: Periorbital tumor location presents a significant challenge with 3-dimensional conformal radiation therapy or intensity modulated radiation therapy due to high tumor dose needed in the setting of close proximity to orbital structures with lower tolerance. Proton beam therapy (PBT) is felt to be an effective modality in such cases due to its sharp dose gradient.
Materials And Methods: We reviewed our institutional PBT registry and identified 17 patients with tumor epicenters within 2 cm of the eye and optic apparatus treated with passive scatter PBT with comparison volumetric arc therapy plans available.
Purpose: Reirradiation in the scalp area can be challenging given the proximity to organs at risk (OARs), such as the eye and brain. Our aim is to evaluate the dosimetric differences of volumetric modulated arc therapy (VMAT) and electron beam therapy (EBT) compared with 3-dimensional proton beam therapy (PBT).
Patients And Methods: We evaluated a patient with recurrent angiosarcoma of the left temporal scalp after prior surgical resections and radiation therapy to 60 Gy in 30 fractions who needed reirradiation.
Article Synopsis
- A novel FDA-approved in vivo dosimetry device using plastic scintillating detectors was tested in an endorectal balloon for real-time dose measurement during stereotactic body radiotherapy (SBRT) for prostate cancer.
- The system measured delivered doses for a patient receiving 36.25 Gy in 5 fractions, with average measured doses showing a difference of no more than 6% compared to the planned doses, which was primarily attributed to uncertainties in detector placement.
- The study suggests that the in vivo dosimeter enhances safety and confidence in treatment delivery, leading to plans for further evaluation in a prospective clinical trial.
Article Synopsis
- Proton therapy is effective for large, shallow areas but requires multiple matched fields due to beam production limits, making accurate dose planning essential.
- Shifting the patient for field matching necessitates precise positioning within 1-2 millimeters for effective treatment delivery.
- A study using an innovative robotic patient positioner system (RPPS) showed that dosimetric accuracy between treatment planning calculations and measurements was highly consistent, supporting the efficiency of RPPS in proton field matching.
A proton beam delivery system on a gantry with continuous uniform scanning and dose layer stacking at the Midwest Proton Radiotherapy Institute has been commissioned and accepted for clinical use. This paper was motivated by a lack of guidance on the testing and characterization for clinical uniform scanning systems. As such, it describes how these tasks were performed with a uniform scanning beam delivery system.
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