Publications by authors named "F Javier Peinado"
The Benefits of an Integral HAMMAM Experience Combining Hydrotherapy and Swedish Massage on Pain, Subjective Well-Being and Quality of Life in Women with Endometriosis-Related Chronic Pelvic Pain: A Randomized Controlled Trial.
Medicina (Kaunas)
October 2024
Article Synopsis
- - The study evaluated a 4-week 'HAMMAM' therapy program, combining hydrotherapy and Swedish massage, on women with chronic pelvic pain from endometriosis that didn't respond to traditional treatments.
- - In a randomized controlled trial with 44 participants, the 'HAMMAM' group experienced significant improvements in dysmenorrhea (pain with menstruation) and dyspareunia (pain during sex), as well as some enhancements in sleep-related pain interference.
- - Overall satisfaction was high (9.71/10) with no serious health issues reported, although no significant improvements were found in catastrophizing thoughts, overall well-being, or quality of life beyond sleep-related measures.
Background: Perfluoroalkyl substances (PFAS) are environmental contaminants present in a wide range of consumer products and frequently detected in drinking water. They have been linked to adverse reproductive health outcomes in women, but there is limited human evidence on the association of PFAS exposure with endometriosis.
Objective/aim: To explore the association between plasma concentrations of several PFAS, considered individually and as a mixture, and the risk of endometriosis in women of childbearing age.
We aimed to explore the relationship of adipose tissue concentrations of some persistent organic pollutants (POPs) with the risk of endometriosis and the endometriotic tissue expression profile of genes related to the endometriosis-related epithelial-mesenchymal transition (EMT) process. This case-control study enrolled 109 women (34 cases and 75 controls) between January 2018 and March 2020. Adipose tissue samples and endometriotic tissues were intraoperatively collected to determine concentrations of nine POPs and the gene expression profiles of 36 EMT-related genes, respectively.
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- Endometrial cancer is influenced by estrogens and the study investigates the impact of environmental pollutants, specifically xenoestrogens, on this type of cancer.
- The research involved analyzing serum samples from 156 patients with endometrial cancer and 150 control subjects to measure the combined estrogenic activity related to these pollutants.
- Results showed no significant difference in xenoestrogen levels between cases and controls, but indicated a complex relationship between exposure levels and cancer risk, with some associations identified for intermediate exposure categories.
Major concerns have been raised about human exposure to endocrine-disrupting chemicals (EDCs) during pregnancy. Effective methodologies for the assessment of this exposure are needed to support the implementation of preventive measures and the prediction of negative health effects. Meconium has proven a valuable non-invasive matrix for evaluating cumulative exposure to xenobiotics during the last two trimesters of pregnancy.
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