Outcome and complications in patients treated with continuous ambulatory peritoneal dialysis (CAPD) at a single centre during 11 years.

Objective: To evaluate outcome and complications in patients treated with CAPD at our centre a retrospective study was performed.

Methods: Relevant data from all 123 consecutive patients on the CAPD program from 1982 to 1994 were reviewed.

Results: Patient survival after 1, 2, 3 years was 89, 78, 69 and 50% respectively.

Antineutrophil cytoplasmic autoantibodies with myeloperoxidase specificity in a patient with anti-glomerular basement membrane disease.

An unusual case is described of a patient with both anti-glomerular basement membrane (GBM) disease and anti-neutrophil cytoplasmic autoantibodies with myeloperoxidase specificity (MPO-ANCA) presenting with acute renal failure. Four years before a seronegative arthritis of the left wrist was diagnosed. Tests for ANCA by indirect immunofluorescence were repeatedly negative.

[Tubulointerstitial nephritis caused by mesalazine (5-ASA) agents].

In five patients (4 men aged 34, 20, 22 and 29 years, and a woman of 34 years) tubulo-interstitial nephritis developed during treatment with 5-aminosalicylic acid (5-ASA) containing drugs for colitis ulcerosa, proctocolitis or Crohn's disease. Two patients had an impaired renal function before treatment with 5-ASA medication. In all patients there was only an incomplete recovery of renal function after cessation of the therapy.

Familial hypokalemia/hypomagnesemia and chondrocalcinosis.

Objective: Familial occurrence of Bartter's syndrome is well known, but the simultaneous occurrence of hypokalemia/hypomagnesemia and chondrocalcinosis in one family has not been described. We present the clinical, laboratory and radiological findings of a family, in which 7 members were affected by disease.

Methods: A total of 43 members of the family could be interviewed concerning their general health, past diseases and joint complaints.