Publications by authors named "F J Young"
Predicting virus-host associations is essential to determine the specific host species that viruses interact with, and discover if new viruses infect humans and animals. Currently, the host of the majority of viruses is unknown, particularly in microbiomes. To address this challenge, we introduce EvoMIL, a deep learning method that predicts the host species for viruses from viral sequences only.
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- The guideline outlines best practices for diagnosing and managing anogenital herpes in adults in the UK.
- It covers topics such as treatment for the initial outbreak, handling recurrences, and effective therapy options.
- The document also emphasizes the importance of prevention strategies and providing supportive, patient-centered counseling.
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- DOCK8 deficiency is a serious immunodeficiency that can only be treated effectively through allogeneic hematopoietic cell transplantation (HCT), which was tested in a clinical trial using a busulfan-based regimen for its effectiveness and safety.
- The trial involved 36 patients (mostly children and young adults) and aimed to see if HCT could improve their health and immune system within one year, with many achieving over 98% donor chimerism shortly after treatment.
- Results showed 80.6% of participants were alive without new complications after a median follow-up of 7.4 years, and the treatment was generally well-tolerated, although some experienced immune system
Background: While food allergy (FA) can be fatal, the greatest public health impact of FA arguably lies in its detrimental effect on quality of life (FAQOL). Understanding the factors that contribute to FAQOL at different ages is essential to develop personalized interventions that will improve FAQOL.
Objective: To determine the most influential factors that impact FAQOL across ages in well-phenotyped participants with confirmed FA.
Our center launched the first antimicrobial stewardship program in Peru. From 2016 to 2023, the proportion of antimicrobial prescriptions audited increased from 60% to 95%, and 65% to 95% of recommendations were accepted. Vancomycin and meropenem use dropped by 95% and 84%, respectively.
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