[Hypersensitivity reaction to systemic corticosteroids in a hemodialysis patients].

Hypersensitivity reactions are a feared complication of hemodialysis considering their potential for a serious and eventually fatal course. This association could reflect a number of different exposures, including concomitant medications. Like this, systemic steroid-induced hypersensitivity reactions do occur, althought their incidence is extremely rare.

Unsuspected rhabdomyolysis associated with phenytoin.

Case Summary: A case of rhabdomyolysis, in which the etiology could be associated with phenytoin administration is presented and guidelines are described which may assist the early recognition, treatment and prevention of renal failure when such patients are treated in intensive care units. A 46-year-old white man experienced a generalized tonic-clonic seizure at home lasting approximately two minutes. The patient presented with similar crises when seen by the emergency services and had a neurological status of seven points on the Glasgow scale.

Kinetic alteration of theophylline at therapeutic doses.

Objective: To report a case of a patient diagnosed as having bronchial asthma treated with intravenous infusion of theophylline, who presented an episode of altered theophylline metabolism with a disproportionately increase in serum concentrations together with tachycardia and symptoms of intoxication.

Case Summary: A 51-year-old white woman with a history of bronchial asthma was treated with intravenous infusion of theophylline in an Intensive Care Unit. Bayesian pharmacokinetic approach for dose individualization was done and linear kinetics of theophylline were observed.

[Differential diagnosis of acute myocardial infarction caused by electrocution].

Electrical injury can affect many organ systems, it seems that the damage results from the conversion of electrical energy into heat. Electrical injuries to the heart are far less frequent and thus, less known. Additionally, it is very difficult to interpret electrocardiographic and enzymatic changes, which are, in other situations, diagnostic of a myocardial infarction.