Exploring Two Methods of CBV Estimation in Two Groups of Grade III Gliomas with Different Appearance on Post-Contrast T1 Images.

Background: Many studies have used Cerebral Blood Volume (CBV) for gliomas grading and there has been in good agreement between CBV and tumor grade. Almost all of those studies have emphasized the importance of leakage correction due to the underestimation/overestimation of CBV caused by T1/T2* leakage effect in enhanced cases of tumors, especially high grade ones.

Objectives: The aim of this study is to investigate two methods of CBV estimation in two groups of gliomas with the same grade and different appearance on post contrast T1 images (Enhanced vs.