Publications by authors named "F J Pameijer"
Purpose: The NAB2::STAT6 fusion is predominantly associated with solitary fibrous tumors (SFTs) and is utilized in diagnosing SFTs through nuclear STAT6 protein overexpression. Recent studies expanded the phenotypic spectrum of NAB2::STAT6 rearranged neoplasms, including adamantinoma-like and teratocarcinosarcoma-like phenotypes. We report a case of a NAB2::STAT6 rearranged epithelial tumor exhibiting sebaceous differentiation in the parotid gland.
View Article and Find Full Text PDFThe Additional Value of Somatostatin Receptor Positron Emission Computed Tomography ([Ga]Ga-DOTATOC PET/CT) Compared with Magnetic Resonance Imaging of the Head and Neck Region in Paraganglioma Patients: A Pilot Study.
Cancers (Basel)
February 2024
Unlabelled: The Dutch guideline for patients suspected of head and neck paragangliomas (HNPGLs) recommends magnetic resonance imaging (MRI) and/or computed tomography (CT) of the head and neck area. Additionally, it suggests considering additional nuclear imaging. The aim of this study was to evaluate the outcomes of [Ga]Ga-DOTATOC PET/CT compared to MRI in patients with suspected HNPGLs and carriers of genetic variations.
View Article and Find Full Text PDFObjective: This study aims to determine the added value of a geometrically accurate diffusion-weighted (DW-) MRI sequence on the accuracy of gross tumor volume (GTV) delineations, using pathological tumor delineations as a ground truth.
Methods: Sixteen patients with laryngeal or hypopharyngeal carcinoma were included. After total laryngectomy, the specimen was cut into slices.
Article Synopsis
- Sinonasal teratocarcinosarcoma is a rare and aggressive cancer primarily affecting the nasal cavity and surrounding structures, making diagnosis tricky due to its varied tissue types.
- A study of three patients showed common symptoms like nasal obstruction and headaches, with all having advanced disease; treatment varied but included surgery and chemotherapy, yet all patients ultimately died from cancer progression.
- The disease rapidly spreads locally, leading to a poor prognosis, emphasizing the need for comprehensive treatment approaches that combine surgery and radiotherapy to improve outcomes, particularly considering the potential of neoadjuvant therapy.
Squamous cell carcinoma of the nasal vestibule is reported to account for less than one percent of all head and neck malignancies. It lacks a designated WHO ICD-O topography code, and multiple systems are available for the staging of this disease, which results in unwanted variability and the subsequent poor reliability of data. The aim of this study was to evaluate the currently available staging systems for cancer of the nasal vestibule, including the recently introduced classification by Bussu et al.
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