Publications by authors named "F J Mangiacapra"
Contrast-associated acute kidney injury (CA-AKI) remains a serious complication after percutaneous coronary revascularization (PCI), with limited effective preventive strategies especially for diabetic patients. This study aimed to assess the effects of novel antidiabetic agents (NAD), i.e.
View Article and Find Full Text PDFGender-Based Specificities of Fractional Flow Reserve Measurement.
Catheter Cardiovasc Interv
December 2024
Article Synopsis
- The study examines gender differences in the relationship between angiographic findings and fractional flow reserve (FFR) in patients with coronary stenosis.
- Median FFR values were found to be higher in female patients than in male patients, and a 50% diameter stenosis (DS) is identified as the best threshold for detecting ischemic FFR in both genders.
- While a higher DS threshold (≥ 59%) improves lesion classification in females, it also results in a higher rate of false negatives.
Article Synopsis
- Aortic valve calcification (AVC) is examined as a predictor for complications in transcatheter aortic valve implantation (TAVI), with a focus on its impact on intra-annular devices.
- Patients with high AVC have a higher risk of developing mild to severe paravalvular leak (PVL) and conduction disorders requiring pacemaker implantation, indicating AVC's significant role in post-TAVI outcomes.
- The study found that higher AVC levels predict poor 30-day clinical outcomes after TAVI, highlighting the importance of assessing AVC to improve patient management.
Correction: Intentional coronary revascularization versus conservative therapy in patients after peripheral artery revascularization due to critical limb ischemia: the INCORPORATE trial.
Gabor G Toth Marianne Brodmann Sadeek Sidney Kanoun Schnur Stanislaw Bartus Mislav Vrsalovic Fabio Mangiacapra
Clin Res Cardiol
July 2024
Intentional coronary revascularization versus conservative therapy in patients after peripheral artery revascularization due to critical limb ischemia: the INCORPORATE trial.
Gabor G Toth Marianne Brodmann Sadeek S Kanoun Schnur Stanislaw Bartus Mislav Vrsalovic Fabio Mangiacapra
Clin Res Cardiol
July 2024
Article Synopsis
- The INCORPORATE trial aimed to determine if an invasive approach (routine coronary angiography and revascularization) is better than conservative treatment for patients with treated critical limb ischemia.
- Conducted as a randomized study, it compared outcomes between patients receiving optimal medical therapy versus those undergoing invasive procedures, measuring myocardial infarction and mortality over one year.
- Results showed similar rates of heart attacks and death in both groups, but the conservative approach had a trend toward higher major adverse cardiac events, suggesting potential benefits of the invasive strategy for some patients.