In RA in remission for >1 y, tapering TNFi to discontinuation did not meet noninferiority criteria compared with stable TNFi for disease flare at 12 mo.

Lillegraven S, Paulshus Sundlisaeter N, Aga AB, et al. Ann Rheum Dis. 2023;82:1394-1403.

[Clinical study and hormonal evaluation of a 48, XXYY male. Comparison with previously published cases].

A new case of the infrequent 48, XXYY syndrome is presented. The somatomedin C and HGH values were high, perhaps playing a role in the above of the mean height of Klinefeter patients, of which this cromosomic abnormality is a variant.