Ubiquitination of OsCSN5 by OsPUB45 activates immunity by modulating the OsCUL3a-OsNPR1 module.

The COP9 signalosome (CSN) is a highly conserved protein complex in eukaryotes, with CSN5 serving as its critical catalytic subunit. However, the role of CSN5 in plant immunity is largely unexplored. Here, we found that suppression of in rice enhances resistance against the fungal pathogen and the bacterial pathogen pv.

AGA Clinical Practice Update on Management of Portal Vein Thrombosis in Patients With Cirrhosis: Expert Review.

Description: Portal vein thromboses (PVTs) are common in patients with cirrhosis and are associated with advanced portal hypertension and mortality. The treatment of PVTs remains a clinical challenge due to limited evidence and competing risks of PVT-associated complications vs bleeding risk of anticoagulation. Significant heterogeneity in PVT phenotype based on anatomic, host, and disease characteristics, and an emerging spectrum of therapeutic options further complicate PVT management.

The morphology and molecular mechanisms of enhanced olfaction in the grain aphid Sitobion miscanthi.

Winged aphids develop more sensitive olfaction than the wingless phenotype to identify potential habitat from afar. Two types of olfactory sensilla, primary rhinarium (PRh) and secondary rhinarium (SRh) are responsible for aphid olfactory perception, of which, SRh is involved in the perception of both E-β-farnesene (EBF) and plant volatiles. Odorant binding proteins (OBPs) play a vital role in the response of insect olfactory nerves located in the rhinarium to external odor stimuli.

Complete genome sequence of a novel iflavirus from wheat sawfly (Dolerus tritici).

Little is known about the insect viruses in wheat sawfly, Dolerus tritici, which is an important agricultural insect feeding on wheat leaves. Here, we used RNA sequencing to identify a novel single positive-strand RNA virus from the larvae of wheat sawfly collected in northern China and then determined its complete genome sequence by rapid amplification of cDNA ends. The complete genome is 9,594 nt in length, including a polyA tail at its 3' terminus, and it is predicted to encode a 326.