Publications by authors named "F J Escudero"

We study the entanglement harvesting between two identical buckled honeycomb lattices placed inside a planar microcavity. By applying time dependent perturbation theory, we obtain quantum correlations between both layers induced by the cavity field. Considering the vacuum state as the initial state of the cavity field and tracing out the time-evolved degrees of freedom, we analyze the entanglement formation using the concurrence measure.

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Context: DNA mismatch repair (MMR) deficiency (dMMR) testing is now recommended in endometrial cancer. Defect identification in the molecules participating in this pathway, or the presence of microsatellite instability, are commonly employed for this purpose. Novel methods are continuously evolving to report dMMR/microsatellite instability and to easily perform routine diagnoses.

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Background & Aims: A blood-based colorectal cancer (CRC) screening test may increase screening participation. However, blood tests may be less effective than current guideline-endorsed options. The Centers for Medicare & Medicaid Services (CMS) covers blood tests with sensitivity of at least 74% for detection of CRC and specificity of at least 90%.

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Article Synopsis
  • Angiosarcoma is a rare type of cancer that arises from the cells lining blood vessels, and current treatments for it are not very effective, making the search for new therapies important.
  • Researchers developed and studied cell line models in both 2D and 3D cultures to understand how the cancer cells grow and spread, proving these models useful for research in angiosarcoma.
  • A drug screening identified 8-amino adenosine as a promising candidate, showing effectiveness in reducing cell growth and invasion at low doses, but it didn't work better in combination with established cancer drugs like paclitaxel or gemcitabine.
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Article Synopsis
  • * The study compared different methods for determining MMR status, including immunohistochemistry (IHC), PCR-based microsatellite instability (MSI) analysis, and targeted genetic sequencing, using 126 early-stage EC samples.
  • * Results showed that over half of the samples were deficient in MMR, with inconsistencies noted among testing methods, particularly between IHC and MSI assessments, highlighting the need for further research to find the best testing approach.
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