Publications by authors named "F J Bruns"
Background: Medical students and doctors face various challenges in clinical practice. Some of these challenges are related to ethical issues. Therefore, teaching ethics respectively building moral competences has become an integral part of the medical curriculum in Germany and many other countries.
View Article and Find Full Text PDFCardiac arrhythmias are a common cardiac condition that might lead to fatal outcomes. A better understanding of the molecular and cellular basis of arrhythmia mechanisms is necessary for the development of better treatment modalities. To aid these efforts, various mouse models have been developed for studying cardiac arrhythmias.
View Article and Find Full Text PDFBackground: Although atrial inflammation has been implicated in the pathophysiology of atrial fibrillation (AF), the identification of atrial inflammation remains challenging. We aimed to establish a positron emission tomography/computed tomography (PET/CT) protocol with Fluor-labeled fluorodeoxyglucose (F-FDG) for the detection of atrial hypermetabolism as surrogate for inflammation in AF.
Methods: We included n = 75 AF and n = 75 non-AF patients undergoing three common PET/CT protocols (n = 25 per group) optimized for the detection of (a) inflammation and (b) malignancy in predefined fasting protocols, and (c) cardiac viability allowing for maximized glucose uptake.
Article Synopsis
- Pulsed-field ablation (PFA) is a new way to treat a heart condition called atrial fibrillation without heating the tissue, unlike older methods.
- In a study with patients who had either PFA or cryoballoon ablation (CBA), they found that PFA caused less activation in certain cells in the heart compared to CBA.
- The results suggest that PFA may be safer and cause less damage, making it important for doctors to understand how different treatments work.