Publications by authors named "F J Brenes Bermudez"
Article Synopsis
- The Cucurbitaceae family, known for its bioactive compounds, is being studied for its potential in preventing and treating colorectal cancer (CRC).
- Four different extracts from cucurbit leaves and seeds were tested on various CRC cell lines to evaluate their effects on tumor growth and cell health.
- Cold ethanolic extracts showed significant anti-cancer properties, such as inhibiting cell proliferation and angiogenesis, and were linked to specific cell cycle changes and gene expression modifications, suggesting they could enhance CRC treatment strategies.
Importance: Polygenic risk scores (PRSs) for coronary heart disease (CHD) are a growing clinical and commercial reality. Whether existing scores provide similar individual-level assessments of disease susceptibility remains incompletely characterized.
Objective: To characterize the individual-level agreement of CHD PRSs that perform similarly at the population level.
The increasing prevalence of childhood obesity worldwide is a significant concern due to its link to severe health issues in adulthood, such as non-communicable diseases (NCDs). To address this issue, this review evaluates the effectiveness of various preventive measures for childhood obesity, focusing on maternal nutrition and breastfeeding. The study underscores the criticality of the periconceptional period, where the diets of both parents can influence epigenetic modifications that impact the child's metabolic pathways and obesity risks.
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