Publications by authors named "F J Alonso Moreno"
Refractance window drying is an emerging technology that allows the development of new dried foods with an acceptable shelf life from products widely consumed in the world with high nutritional content and health benefits, such as Dairy products. The present study aimed to determine the effect of temperature and product thickness during Refractance window drying in a laboratory scale dryer on the physicochemical properties of whole bovine milk and commercial flavored yogurt, using an optimal design model. The drying temperature range was between 40°C and 80°C, while the evaluated thickness ranged from 1 to 3 mm.
View Article and Find Full Text PDFStandard treatments in hormone receptor-positive (HR+)/HER2-metastatic breast cancer (mBC) typically involve endocrine therapy (ET) combined with CDK4/6 inhibitors, yet resistance to ET remains a persistent challenge in advanced cases. A deeper knowledge of the use of liquid biopsy is crucial for the implementation of precision medicine in mBC with real-time treatment guidance. Our study assesses the prognostic value of and mutations in DNA derived from extracellular vesicles (EV-DNA) in longitudinal plasma from 59 HR+/HER2-mBC patients previously exposed to aromatase inhibitors, with a comparative analysis against circulating tumor DNA (ctDNA).
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- A study was conducted to investigate the X-chromosome's role in Alzheimer's Disease (AD), which had been overlooked in previous genome-wide association studies.
- The research included 115,841 AD cases and 613,671 controls, considering different X-chromosome inactivation (XCI) states in females.
- While no strong genetic risk factors for AD were found on the X-chromosome, seven significant loci were identified, suggesting areas for future research.
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- ω-3 polyunsaturated fatty acids, especially docosahexaenoic acid (DHA), are vital for brain health, but excessive DHA can lead to oxidative stress in the brain.
- A study on male rats showed that a 10-week diet with high-DHA fish oil improved antioxidant defenses and reduced protein carbonylation in brain regions compared to oils with lower DHA levels.
- Findings revealed that the cerebellum is more affected by dietary fat composition than the cortex, suggesting that high DHA intake enhances the brain's ability to cope with oxidative damage.
Malnutrition is a global issue linked to energy or nutrient imbalances, often resulting in deficiencies or overweight. Dairy products, rich in macronutrients and micronutrients, are a potential solution. However, processing, storage, and digestion can lead to nutrient loss.
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