Publications by authors named "F Isa"
Objective: The aim of this study was to assess hearing level of preschoolers with delayed speech in order to detect any underlying hearing loss Methods: In this research we targeted preschool children with speech delay, who have not been previously diagnosed with any medical or psychological illnesses. A total of 54 preschool speech-delayed children were audiologically assessed in our clinic in the past year. The age at time of referral ranged from two to 7.
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- The study investigates how antiviral monoclonal antibodies (mAbs), particularly casirivimab and imdevimab (CAS+IMD), affect immune responses when individuals are vaccinated against SARS-CoV-2 after receiving mAb treatment.
- It was found that the presence of CAS+IMD during vaccination reduced the effectiveness of the vaccine in generating neutralizing antibodies, though other immune responses remained intact.
- This reduction in antibody production is linked to "epitope masking," but can be reversed with booster shots, and influences the immune response differently in those who had not yet begun their natural immunity when treated with mAbs.
Article Synopsis
- The study examines the link between anxiety, depression, and gastrointestinal (GI) symptoms in university students through a campus-wide survey.
- A total of 437 students from three public medical universities in Saudi Arabia participated, using standardized measures for mental health and a tailored questionnaire for GI symptoms.
- Results showed a significant correlation between high levels of anxiety and depression with GI issues, indicating the need for integrated health interventions to support both mental and physical well-being among students.
Effect of timing of casirivimab and imdevimab administration relative to mRNA-1273 COVID-19 vaccination on vaccine-induced SARS-CoV-2 neutralising antibody responses: a prospective, open-label, phase 2, randomised controlled trial.
Lancet Infect Dis
January 2025
Background: Deeper insight is needed on how monoclonal antibodies (mAbs) affect vaccine-mediated immune responses when targeting the same protein. We describe the first prospective randomised trial designed to understand mAb-mediated alterations in vaccine-induced immune responses to SARS-CoV-2 spike protein epitopes.
Methods: This randomised, open-label, parallel-group study assessed the potential interaction of a mAb combination, casirivimab and imdevimab, with a vaccine, Moderna's mRNA-1273, in healthy SARS-CoV-2 immunologically naive, seronegative adults at six centres in the USA.
The mission of the JT-60SA project is to complement ITER's capabilities by addressing the fundamental physics and engineering challenges necessary to develop a practical and reliable fusion power plant. Diagnostics play a pivotal role in achieving this mission, especially the Thomson Scattering (TS) diagnostic systems developed by a collaborative Japan-EU team. The edge Thomson scattering of JT-60SA is tailored to measure the low field side outer region of the plasma, in particular, to resolve the electron temperature Te and density ne.
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