Publications by authors named "F Ingravalle"
Background: Moral Distress (MD) is a unique form of distress that occurs when people believe they know the ethically correct action to take but are constrained from doing so. Limited clinical experience and insufficient ethical knowledge contribute to nursing students' MD, which can potentially cause negative outcomes. The aims of this study are: (1) to describe the MD intensity of nursing students, and (2) to analyze differences and associations between MD intensity and socio-demographic and academic variables.
View Article and Find Full Text PDFParkinson's disease (PD) is defined by progressive worsening of gait, posture, and balance, as well as disability in daily life activities, and improvement in chronic musculoskeletal pain, particularly neck pain associated with worsening of balance. The study's goal is to look into the relationship between scoliosis, balance, and cervical pain in Parkinson's disease patients. Cross-sectional, pilot study.
View Article and Find Full Text PDFIn accordance with U.S. FDA Foods Program Regulatory Science Steering Committee guidelines, with this study, we optimized and validated a commercial real-time PCR method for the detection of low amounts of lupin in four classes of food matrices: chocolate cookies, ragù, Olivier salad, and barley and rice flour.
View Article and Find Full Text PDFArticle Synopsis
- The SOD1 gene is linked to motor neuron degeneration in familial amyotrophic lateral sclerosis (ALS), and previous rodent studies have not yet led to effective human therapies or early biomarkers.
- Researchers have created a transgenic pig model with the hSOD1 gene, which mirrors human ALS progression, to explore early disease mechanisms and potential diagnostic markers.
- The study found that oligodendrocytes in the spinal cords of these pigs show early activation, followed by astrocyte and microglia activation, with changes in extracellular vesicle (EV) production indicating earlier signs of disease before symptoms arise.
Article Synopsis
- * Conducted at Santo Spirito Hospital over six months, data was collected from admissions to analyze discharge requests and exclusion of surgical and ICU cases; 1222 admissions were reviewed, with 16% showing an average delay of 6.3 days.
- * The findings reveal that delayed discharges contribute to overcrowding in emergency departments, increased healthcare costs, and inefficient use of hospital beds, with the study noting that initial clinical conditions do not reliably predict discharge delays.