Publications by authors named "F Inci"
Article Synopsis
- Gastrointestinal (GI) barrier dysfunction is a critical early indicator of multiple complex diseases, but current testing methods for saccharide molecules used to assess this function are expensive and time-consuming.
- A new one-component system utilizing a naphthyl-pyridine core and boronic acid receptor has been developed for the early detection of saccharide biomarkers like lactulose, which indicates GI barrier issues.
- The innovative design incorporates a scalable 96-well format with gold nanoparticles and combines plasmonics and fluorescence for sensitive lactulose quantification, aiming to create an affordable and portable diagnostic tool for routine GI permeability testing.
Article Synopsis
- Diverse analytical techniques are needed to study microplastics (MPs) since current methods struggle to detect smaller sizes, particularly those under 5 μm.
- The study introduces a new method called MicroMetaSense, which uses metal-enhanced fluorescence to detect a wide range of MPs at extremely low concentrations, achieving a sensitivity of 183-205 femtograms.
- This approach is cost-effective, efficient, and significantly improves detection capabilities, marking a significant advancement in monitoring microplastics in both lab and environmental samples.
Inflammatory bowel disease (IBD) comprises chronic inflammatory conditions with complex mechanisms and diverse manifestations, posing significant clinical challenges. Traditional animal models and ethical concerns in human studies necessitate innovative approaches. This review provides an overview of human intestinal architecture in health and inflammation, emphasizing the role of microfluidics and on-chip technologies in IBD research.
View Article and Find Full Text PDFThe COVID-19 pandemic raised fears about a rise in prolonged grief rates. To determine if these fears are justified, we examined an online sample of 329 Turkish adults for their level of prolonged grief symptoms (as well as probable Prolonged Grief Disorder-PGD) and associated factors in relation to losses during the pandemic. Respondents completed measures of prolonged grief, post-traumatic stress disorder, and depression.
View Article and Find Full Text PDFIntroduction: We compared the efficacy of first-generation granisetron and second-generation palonosetron in triplet anti-emetic prophylaxis in patients with non-small cell lung cancer (NSCLC) receiving cisplatin-based high emetogenic chemotherapy (HEC).
Methods: This prospective, multicenter, non-randomized, observational study was conducted between June 2018 and December 2021. Patients diagnosed with NSCLC who received triplet anti-emetic prophylactic treatment with aprepitant and dexamethasone plus granisetron or palonosetron before the first cycle of chemotherapy were included in the study.