[The effect of local chemical sympathectomy of the rat uterus on its sensitivity to sex hormones].

Chemical sympathectomy of the rat uterus did not alter the main metabolic processes maintaining the uterus weight even though it changed its response to sex steroids. Sensitivity of endo- and myometrium to progesterone significantly decreased thus inducing a relative increase in the estradiol action.

[Early chemical sympathectomy and the function of the hypophyseal-gonadal system in sexually immature and adult female rats].

Early chemical desympathisation with 6-hydroxydopamine decreased the contents of the follicle-stimulating hormone in the blood serum of 1-month old rats. The steroidogenesis disturbances were more obvious in sexually immature rats in the general desympathisation. In sexually mature rats, these disturbances disappeared.

[The effect of postnatal sympathectomy on the production and receptor binding of sex steroids in female rats during puberty].

The total chemical desympathization caused by injection of 6-hydroxydopamine in the first day of life increased the progesterone secretion, decreased the estradiol secretion and abolished translocation of estradiol receptors to the cell nuclei in the uterus of 1-2 days old rats, which correlated with the absence of uterus weight increase after exogenous estradiol injections. The peripheral desympathization caused by injection of neurotoxin to two weeks old rats induced only estradiol secretion decrease, but to the less extent than after total desympathization.