Publications by authors named "F I Ataullakhanov"
Macromolecular assembly depends on tightly regulated pairwise binding interactions that are selectively favored at assembly sites while being disfavored in the soluble phase. This selective control can arise due to molecular density-enhanced binding, as recently found for the kinetochore scaffold protein CENP-T. When clustered, CENP-T recruits markedly more Ndc80 complexes than its monomeric counterpart, but the underlying molecular basis remains elusive.
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- Umbilical cord blood's use in hemostasis testing for newborns is under-researched, leading to this study aimed at evaluating its applicability compared to venous blood samples.
- The study involved 187 newborns and found that umbilical cord blood exhibited a hypocoagulable shift in clotting times and fibrinogen levels, while thromboelastometry and thrombodynamics showed a hypercoagulable shift in newborn blood.
- The differences in hemostatic parameters highlight that newborns have distinct coagulation profiles compared to adults, with implications for understanding their physiological and pathological hemostatic features.
Aging is interrelated with changes in red blood cell parameters and functionality. In this article, we focus on red blood cells (RBCs) and provide a review of the known changes associated with the characterization of RBC deformability in aging and related pathologies. The biophysical parameters complement the commonly used biochemical parameters and may contribute to a better understanding of the aging process.
View Article and Find Full Text PDFMacromolecular assembly depends on tightly regulated pairwise binding interactions that are selectively favored at assembly sites while being disfavored in the soluble phase. This selective control can arise due to molecular density-enhanced binding, as recently found for the kinetochore scaffold protein CENP-T. When clustered, CENP-T recruits markedly more Ndc80 complexes than its monomeric counterpart, but the underlying molecular basis remains elusive.
View Article and Find Full Text PDFThe hematological effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are important in COVID-19 pathophysiology. However, the interactions of SARS-CoV-2 with platelets and red blood cells are still poorly understood. There are conflicting data regarding the mechanisms and significance of these interactions.
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