[Value of mexiletine in the treatment of Thomsen-Becker myotonia].

The case of a 1 month-old boy with a severe form of Thomsen-Becker myotonia is reported. Resistance to regular antimyotonic treatment over a 3 month-period of time led to use mexiletine, an antiarrhythmic drug. This treatment was responsible for a dramatic clinical and electromyographic improvement.

[Perioperative management of 98 cases of type C esophageal atresia (1970-1980) ].

We report our experience about 98 cases of type C esophageal atresia admitted to our unit from 1970 to 1980. 78.6% underwent successful anastomosis; 65.

[Puberty and adult height in congenital virilizing adrenal hyperplasia (author's transl)].

A study of 52 pubertal patients having been treated for virilizing adrenal hyperplasia (38 females and 14 males) leads to emphasize the importance of the precocity and accuracy of treatment. In patients with delayed treatment, mainly when they are girls, an advanced or true precocious puberty will increase the advance of bone age and reduce adult height. But, whatever be the time of onset of treatment and of pubertal achievement, no important or sustained sexual improvement was found in patients receiving a well-controlled treatment.

[Hemineurine: an always present hazard in children].

Chlormethiazole, a hypnotic and sedative drug that selectively inhibits the cerebral cortex is occasionally used in status epilepticus in children. A child aged 18 months is described who developed toxic side effects. This drug, given as an alcoholic solution is highly toxic if used inappropriately.