Publications by authors named "F Higa"

Article Synopsis
  • * The present study validated the score's effectiveness by comparing 116 patients with L. pneumophila CAP to 947 patients with SARS-CoV-2 Omicron CAP, finding that L. pneumophila scores were significantly higher (4 vs 1).
  • * Diagnostic sensitivity and specificity for L. pneumophila CAP were notably high (90.5% sensitivity and 90.8% specificity) when using a cutoff score of ≥3 points, emphasizing the score's reliable diagnostic potential during
View Article and Find Full Text PDF
Article Synopsis
  • - The study examined the clinical characteristics and risk factors associated with severe COVID-19 cases caused by the XBB variant in Okinawa, Japan, during mid-2023.
  • - Out of 367 hospitalized patients, 18.5% were classified as severe, with older age and underlying health conditions linked to a higher mortality rate (13.2% in severe cases vs. 3.0% in mild cases).
  • - Notably, diabetes mellitus increased the risk for severe COVID-19, while receiving the bivalent omicron booster significantly reduced the severity of the disease.
View Article and Find Full Text PDF

Objective: Epidemiological information is essential in providing appropriate empiric antimicrobial therapy for pneumonia. This study aimed to clarify the epidemiology of community-acquired pneumonia (CAP) by conducting a systematic review of published studies in Japan.

Design: Systematic review.

View Article and Find Full Text PDF

Introduction: Aspiration pneumonia is increasingly recognised as a common condition. While antibiotics covering anaerobes are thought to be necessary based on old studies reporting anaerobes as causative organisms, recent studies suggest that it may not necessarily benefit prognosis, or even be harmful. Clinical practice should be based on current data reflecting the shift in causative bacteria.

View Article and Find Full Text PDF

Invasive meningococcal disease persists as a fulminant disorder worldwide. Although cases caused by Neisseria meningitidis serogroup X (MenX) occur infrequently, outbreaks have been reported in countries in Africa in recent decades. We report 2 cases of MenX invasive meningococcal disease in São Paulo, Brazil, in 2021 and 2022, during the COVID-19 pandemic.

View Article and Find Full Text PDF