Publications by authors named "F Haziza"

Article Synopsis
  • Lung cancer is a leading cause of cancer-related deaths, and France currently lacks a national screening program for it.
  • The Foch Hospital launched a pilot program for low-dose CT screening to assess its effectiveness, targeting individuals aged 50-80 with significant smoking histories.
  • Out of 477 participants, a small percentage (1.7%) showed positive nodules on scans, with the majority of detected cancers (66.7%) found at early stages, indicating the feasibility of structured screening in identifying treatable cases.
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The European Genome-phenome Archive (EGA - https://ega-archive.org/) is a resource for long term secure archiving of all types of potentially identifiable genetic, phenotypic, and clinical data resulting from biomedical research projects. Its mission is to foster hosted data reuse, enable reproducibility, and accelerate biomedical and translational research in line with the FAIR principles.

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Motivation: The majority of genome analysis tools and pipelines require data to be decrypted for access. This potentially leaves sensitive genetic data exposed, either because the unencrypted data is not removed after analysis, or because the data leaves traces on the permanent storage medium.

Results: : We defined a file container specification enabling direct byte-level compatible random access to encrypted genetic data stored in community standards such as SAM/BAM/CRAM/VCF/BCF.

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During the last decade there has been a craze for the percutaneous edge-to-edge mitral valve repair technique with the Mitra-Clip device. This is an alternative treatment to mitral valve surgery for severe mitral regurgitation. In France, this device is aimed at poor candidates for mitral valve surgery.

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