Publications by authors named "F Hartnell"
NPJ Vaccines
October 2020
Article Synopsis
- Simian adenoviral and modified vaccinia Ankara (MVA) viral vectors are being tested for their effectiveness as vaccine carriers that induce T cell responses against various infections and cancers, but it’s uncertain if these responses can be improved with additional doses over time.*
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- A study involving healthy volunteers demonstrated that reboosting with ChAd3-NSmut/MVA-NSmut vaccines either 8 weeks or 1 year after the first doses was safe, but the timing affected T cell response, with longer intervals resulting in better memory response activation.*
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- The researchers found that a reduced dose of MVA-NSmut (ten-fold lower) still produced strong and effective T cell responses against Hepatitis C virus
