Publications by authors named "F Hammer"
A method for the anonymization of time-continuous data, which preserves the relation between the time- and value dimension is proposed in this work. The approach protects against linking- and distribution attacks by providing k-anonymity and t-closeness. Distributions can be generated from given sets using Distribution Clustering, according to the similarity of the curves, which serve as a replacement for the population distribution.
View Article and Find Full Text PDFBackground And Aims: Two or more National Institutes of Health Stroke Scale (NIHSS) points on each motor items (AL score) have shown good accuracy in predicting large vessel occlusion (LVO) in the prehospital setting of acute ischemic stroke (AIS) care. We aimed to study this score for LVO prediction in our stroke network and predictors of poor outcome (PO) after mechanical thrombectomy (MT).
Methods: From our Safe Implementation of Thrombolysis in Stroke (SITS) registry including patients receiving reperfusion therapy for AIS, we retrospectively computed the AL score from the admission NIHSS to test the diagnostic accuracy for LVO prediction.
Purpose: To investigate the level of cellular senescence in stem cells derived from microfragmented abdominal adipose tissue harvested from patients with knee osteoarthritis (OA).
Methods: Stem cells harvested from microfragmented abdominal adipose tissue from 20 patients with knee OA, aged 29-65 years (mean = 49.8, SD = 9.
Article Synopsis
- Common capillary malformations typically involve mutations in GNAQ or GNA11, but this study found other genetic causes by analyzing 82 lesions for mutations in PIK3R1 and PIK3CA.
- The researchers identified 9 somatic pathogenic variants that led to a specific phenotype, characterized by pale capillary malformations with visible dilated veins and abnormal signaling pathways related to disease development.
- Using zebrafish embryos, they demonstrated that these mutations affect vascular development, and highlighted that the elevated Akt signaling caused by the mutations can be countered by specific inhibitors, paving the way for potential targeted treatments.
Late thrombosis of the renal graft vein is a rare complication that results in graft loss in the majority of cases. We describe the case of a 57-year-old female patient who had a kidney transplant 32 years ago and developed a late thrombosis of the graft vein, accompanied by extensive thrombosis in the common femoral and iliac veins. Risk factors included severe malnutrition, chronic inflammation due to an anal fistula, and Cockett syndrome.
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