Publications by authors named "F H Zaidi"

Malaria remains a major health challenge in developing countries, with climate change intensifying its impact. Pakistan is among the most vulnerable nations. This study examines the relationship between temperature and malaria cases in two highly affected districts, Bannu and Lakki Marwat, to inform climate-adaptive interventions.

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Background: Medical student-led health promotion projects are pivotal in enhancing community health and medical education. However, research focusing on the impact of such projects on medical students' knowledge translation skills is limited. This study aims to address this gap by developing and validating a survey tool to assess the knowledge translation skills and overall impact of a student-led health promotion project.

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This article explores the correlation between vitamin D levels and cardiovascular health, focusing on hypertension, atherosclerosis, and cardiac dysfunction. Cardiovascular diseases (CVDs) rank as the leading global cause of death, underscoring the significance of exploring vitamin D's potential role in maintaining a healthy cardiovascular system. It discusses vitamin D's mechanisms of action, including genomic and non-genomic pathways, and explores risk factors like smoking, obesity, and hypertension, linked to vitamin D deficiency.

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Article Synopsis
  • Septic shock leads to over 40% mortality, transitioning from early hyper-inflammation to hypo-inflammation, making patients vulnerable to secondary infections.
  • The study examines how plasma metabolites from septic shock patients impact immune responses, focusing on cell stimulation with E. Coli lipopolysaccharide (LPS) and plasma metabolomics.
  • Findings reveal that septic shock patients show endotoxin tolerance and significant accumulation of various metabolites, which can either suppress or enhance the inflammatory response of immune cells.
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Short-chain fatty acids (SCFAs) are essential molecules produced by gut bacteria that fuel intestinal cells and may also influence overall health. An imbalance of SCFAs can result in various acute and chronic diseases, including diabetes, obesity and colorectal cancer (CRC). This review delves into the multifaceted roles of SCFAs, including a brief discussion on their source and various gut-residing bacteria.

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