Itraconazole in the treatment of tinea pedis and tinea manuum: comparison of two treatment schedules.

A multicentre, randomized, double-blind, parallel-group trial was conducted to compare the efficacy and safety of two dosages of itraconazole in the treatment of tinea pedis or manuum. Of the 135 patients recruited, 66 received itraconazole 400 mg daily for 1 week and 69 received itraconazole 100 mg daily for 4 weeks. In the evaluable patients observed-case analysis, mycological cure was seen in 63% of patients in the 400 mg/1 week group and in 75% in the 100 mg/4 weeks group at the end of a 6-week follow-up period (not significantly equivalent).

Factors influencing participation among melanoma screening attenders.

We surveyed the demographic profile and motives prompting to participate among people attending voluntary melanoma screening clinics in Southern Limburg, the Netherlands, in June 1993. Precampaign public announcements addressed only melanoma and its precursor lesions. All attendees completed a detailed questionnaire addressing demographic particulars and specific fixed choice questions on their motivation to attend.

Volunteer melanoma screenings. Follow-up, compliance, and outcome.

Background: Follow-up information on free melanoma screening clinics is not readily available.

Objective And Methods: We studied the follow-up, compliance, and outcome of positive screenees after a screening campaign for melanoma in the Netherlands.

Results: Of the 4146 participants, 486 (11.

Total skin examination during screening for malignant melanoma does not increase the detection rate.

Total skin examination during public screening for malignant melanoma is often advocated, but the benefit of this approach has not been established properly. We assessed the yield of examination of the entire skin, in addition to examination of intentionally shown skin lesions, in people attending melanoma screening clinics in southern Limburg, the Netherlands, in 1993. Of the 4146 attenders, 2910 (70%) showed a specific skin spot.