Publications by authors named "F H Hetzer"
Article Synopsis
- The S2k guideline for hidradenitis suppurativa/acne inversa (HS/AI) serves as a decision aid for selecting effective treatments for this chronic skin condition, which is characterized by painful lesions in areas rich in apocrine glands.
- The condition shows a prevalence of 0.3% in Germany, often diagnosed with a significant delay of about 10 years, and can severely impact a patient's quality of life due to the painful and recurrent nature of the disease.
- Treatment options include various medications like oral tetracyclines and biologics such as adalimumab, with a focus on assessing disease severity using tools like the International Hidradenitis Supp
Structure-Based Evolution of G Protein-Biased μ-Opioid Receptor Agonists.
Angew Chem Int Ed Engl
June 2022
The μ-opioid receptor (μOR) is the major target for opioid analgesics. Activation of μOR initiates signaling through G protein pathways as well as through β-arrestin recruitment. μOR agonists that are biased towards G protein signaling pathways demonstrate diminished side effects.
View Article and Find Full Text PDFAim: Training in colorectal surgery across Europe is not yet standardized. The European Board of Surgical Qualification (EBSQ) coloproctology examination has been held annually since 1998. The aims of this study were to illustrate the current situation of coloproctology specialization in Europe and to analyse the EBSQ examinations held over the last 20 years.
View Article and Find Full Text PDFBackground/aims: The aim of this study was to evaluate the sustainability of sacral neuromodulation (SNM) success in patients with fecal incontinence (FI) and/or constipation.
Methods: This is a retrospective analysis of a prospective database of patients who received SNM therapy for FI and/or constipation between 2006 and 2015. Success rates, complications and reintervention rates were assessed after up to 10 years of follow-up.
Aim: The aim of this official guideline published by the German Society of Gynecology and Obstetrics (DGGG) and coordinated with the German Society of Urology (DGU) and the German Society of Reproductive Medicine (DGRM) is to provide consensus-based recommendations, obtained by evaluating the relevant literature, on counseling and fertility preservation for prepubertal girls and boys as well as patients of reproductive age. Statements and recommendations for girls and women are presented below. Statements or recommendations for boys and men are not the focus of this guideline.
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