Publications by authors named "F Guzman"

Haemocyanin-derived peptides were previously found in semi-purified fractions of mucus secretion from the snail Achatina fulica, which exhibited an inhibitory effect on Staphylococcus aureus strains. Here, an in silico rational design strategy was employed to generate new antimicrobial peptides (AMPs) from A. fulica haemocyanin-derived peptides (AfH).

View Article and Find Full Text PDF

In Chile, Atlantic salmon and rainbow trout face significant production challenges due to the presence of Flavobacterium psychrophilum, which generates severe disease issues and economic losses. To address this, the salmon industry relies on vaccines and antibiotics, the latter raising concerns about bacterial resistance. For that reason, our study explores an alternative strategy for controlling F.

View Article and Find Full Text PDF
Article Synopsis
  • - Antimicrobial peptides (AMPs) play a crucial role in innate immunity and have various functions, making them promising alternatives to traditional antibiotics, especially as antibiotic resistance rises.
  • - The study discovered a new peptide, AXOTL-13, using transcriptome data, confirmed its antibacterial properties through PCR and synthesis, and found it effectively inhibits bacterial growth without harming red blood cells.
  • - This research is groundbreaking in identifying and evaluating the antimicrobial activity of peptides, specifically AXOTL-13, and it lays the groundwork for future studies in the field.
View Article and Find Full Text PDF
Article Synopsis
  • Non-typhoidal Salmonella (NTS) is a major cause of foodborne outbreaks globally, especially in countries like Peru, necessitating an analysis of its circulating serotypes.
  • Researchers studied the genomes of 1122 NTS strains from 1998 to 2018, identifying 40 different Sequence Types (STs), with ST-32 and ST-11 being the most prevalent.
  • The study revealed that strains within the same ST are genetically similar and that certain virulence factors and drug resistance are strongly associated with these common STs, indicating their adaptation in the region.
View Article and Find Full Text PDF
Article Synopsis
  • * Researchers used advanced electron energy loss spectroscopy to identify new optical phonon modes that strongly interact with electrons, which are primarily due to vibrations of oxygen atoms in the interface layers.
  • * The results indicate a direct relationship between the strength of electron-phonon coupling and the distance between FeSe and the TiO-layer in SrTiO, offering insights into improving superconductivity in similar materials.
View Article and Find Full Text PDF