Publications by authors named "F Guerrera"
Background: Exercise-induced bronchoconstriction (EIB) is common in children with asthma but can be present also in children without asthma, especially athletes. Differential diagnosis includes several conditions such as exercise-induced laryngeal obstruction (EILO), cardiac disease, or physical deconditioning. Detailed medical history, clinical examination and specific tests are mandatory to exclude alternative diagnoses.
View Article and Find Full Text PDFImproved Event-Free Survival After Complete or Major Pathologic Response in Patients With Resectable NSCLC Treated With Neoadjuvant Chemoimmunotherapy Regardless of Adjuvant Treatment: A Systematic Review and Individual Patient Data Meta-Analysis.
Daniele Marinelli Antonio Nuccio Alessandro Di Federico Francesca Ambrosi Pietro Bertoglio Francesco Guerrera
J Thorac Oncol
October 2024
Article Synopsis
- Neoadjuvant chemoimmunotherapy is changing the treatment for resectable non-small cell lung cancer (NSCLC), but the importance of pathologic response is still uncertain.
- A systematic review and individual patient data meta-analysis was conducted to assess how achieving complete pathologic response (pCR) or major pathologic response (MPR) affects long-term survival (EFS) and examine the role of adjuvant immunotherapy.
- The findings showed that patients who achieved pCR or MPR had significantly better EFS rates, while adjuvant immunotherapy did not improve survival outcomes post-surgery.
Article Synopsis
- Radical surgery is the most effective treatment for early-stage lung cancer, with video-assisted thoracic surgery (VATS) being a less painful alternative to traditional surgery methods.
- Current localization techniques for identifying lung cancer are limited, particularly the near-infrared (NIR) indocyanine green (ICG) method, which struggles with deep tissue and lymph node detection.
- This study tests the effectiveness of Cetuximab-IRDye800CW, a combination of a monoclonal antibody and an advanced NIR dye, in accurately marking lung nodules and lymph nodes during VATS for improved detection outcomes.