Publications by authors named "F Gudiol"
Objectives: This study details the accumulated experience of more than 31 years using a low-dose systematic dexamethasone protocol with mannitol and antiseizure prophylaxis for the treatment of suspected pneumococcal meningitis.
Methods: Data have been prospectively collected for the period1977-2018. From 1987, patients with suspected pneumococcal meningitis received 12 mg dexamethasone followed by 4 mg/6 h for 48 h, started before or with the first antibiotic dose.
Leveraging a nationwide infection surveillance program to implement a colorectal surgical site infection reduction bundle: a pragmatic, prospective, and multicenter cohort study.
Int J Surg
April 2023
Article Synopsis
- Bundled interventions for colorectal surgery were analyzed in a nationwide study to determine their effectiveness in reducing surgical site infections (SSI) compared to a control group.
- The study involved 37,849 procedures, revealing that implementing the care bundle reduced overall SSI rates from 18.38% in the control group to 10.17% in the intervention group, showing a significant decrease in infection rates.
- Key components of the bundle, such as laparoscopy, oral antibiotic prophylaxis (OAP), and mechanical bowel preparation, were most effective in lowering both overall SSI and organ/space SSI, highlighting the importance of these practices for improving surgical outcomes.
Penicillin- and Cephalosporin-Resistant Pneumococcal Meningitis: Treatment in the Real World and in Guidelines.
Antimicrob Agents Chemother
December 2022
To report on the therapy used for penicillin- and cephalosporin-resistant pneumococcal meningitis, we conducted an observational cohort study of patients admitted to our hospital with pneumococcal meningitis between 1977 and 2018. According to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) recommendations, we defined pneumococci as susceptible and resistant to penicillin with MIC values of ≤0.06 mg/L and > 0.
View Article and Find Full Text PDFObjectives: Hospital antibiotic consumption is measured using defined-daily-doses (DDD) divided by bed days. However,other denominators as discharges could provide a more accurate interpretation of consumption. The main objective was to analyze trends of antibiotic consumption among hospitals in Catalonia during the period 2008-2016, using both DDD/100 bed days and DDD/100 discharges.
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