Publications by authors named "F Grillet"

Article Synopsis
  • * Skin biopsies from CholU patients showed a decrease in local sweating, but total sweat volume remained the same, and specific tight junction proteins in sweat glands exhibited abnormal distribution.
  • * A new ex vivo skin model has been developed to study sweat secretion in CholU patients, aiming to better understand the mechanisms behind this condition.
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JCO Osimertinib has been established as a standard of care for patients with common sensitizing -mutant advanced non-small-cell lung cancer (NSCLC) although the sequential approach (first-generation inhibitor gefitinib followed by osimertinib) has not been formally compared. The phase II APPLE trial (ClinicalTrials.gov identifier: NCT02856893) enrolled 156 treatment-naïve patients, and two treatment strategies were evaluated: osimertinib up front or the sequential treatment approach with gefitinib up front followed by osimertinib at the time of progression, either molecular progression (detection of plasma T790M resistance mutation) regardless of the radiologic status or just at the time of radiologic progression.

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Purpose: The main objective of this study was to identify risk factors for post-percutaneous transthoracic lung biopsy (PTLB) pneumothorax and to establish and validate a predictive score for pneumothorax occurrence to identify patients eligible for outpatient care.

Material And Methods: Patients who underwent PTLB between November 1, 2012 and March 1, 2017 were retrospectively evaluated for clinical and radiologic factors potentially related to pneumothorax occurrence. Multivariate logistic regression was used to identify risk factors, and the model coefficient for each factor was used to compute a score.

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Purpose: To determine the risk factors for local of adult patients treated for desmoid tumors by cryoablation.

Materials And Methods: Eighty-four patients treated for nonabdominopelvic desmoid tumors by cryoablation from July 2012 to July 2020 were included in a retrospective study. The population was composed of 64 women (76.

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Article Synopsis
  • The study investigated the prevalence and characteristics of sleep apnea (SA) in patients who were hospitalized in the ICU for severe COVID-19, focusing on their apnea hypopnea index (AHI) three months post-illness.
  • Out of 68 patients, a staggering 91% developed SA, with 44 individuals experiencing moderate to severe cases, while 62% of patients had other health issues, like obesity and hypertension.
  • The findings emphasize the need for sleep assessments after ICU care for COVID-19, as those with moderate to severe SA had more severe COVID-19 symptoms and longer hospital stays.
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