Background: Heart transplantation is an effective treatment offering the best recovery in both quality and quantity of life in those affected by refractory, severe heart failure. However, transplantation is limited by donor organ availability. The reintroduction of heart donation after the circulatory determination of death () in 2014 offered an uplift in transplant activity by 30%.
View Article and Find Full Text PDFIntroduction: Elective heart transplantation (HTX) aims to improve physical ability, increase survival, and improve health-related quality of life (HRQoL) in patients with chronic heart failure. Nevertheless, most patients who undergo urgent HTX are previously healthy, and a transplant could be perceived as a limitation. The aim of this study is to compare HRQoL between elective and urgent heart transplant recipients.
View Article and Find Full Text PDFObjective: To show that patients with intertrochanteric fractures treated with a proximal femoral nail have a better postoperative course than those treated with a DHS plate (dynamic hip screw).
Methods: Patients with a Boyd & Griffin type II intertrochanteric fracture were randomly divided into two groups: a group of patients treated with a PFN and another one treated with a DHS plate. All patients were assessed at 2, 4, 8 and 16 weeks using the Harris scale and the visual analog scale pre- and postoperatively, as well as the operative time, incision size, intraoperative bleeding, onset of partial and/or total weight bearing, healing time, time to attain prior physical activity level, and radiographic result.
We experimentally demonstrate an intensity modulated and direct detection optical OFDM with variable bit rate from 5 Gb/s to 9 Gb/s using BPSK format. A fast processing based on the Hartley transform is performed with low complexity DSP, achieving the same performance as 4QAM FFT-based processing. Using the same bandwidth occupancy as required for 5 Gb/s, the bit rate can be increased up to 80% and transmitted over 25 km SSMF, by reducing the guard band and adopting an optimized transceiver design with additional overhead, including half-length training symbols and cyclic extension.
View Article and Find Full Text PDFThis randomized, comparative, multinational phase 3b/4 study of patients 1-8 years postcardiac transplantation (mean 3.9 years) evaluated the effect of conversion from a calcineurin inhibitor (CNI) to sirolimus on renal function in patients with renal insufficiency. In total, 116 patients on CNI therapy with GFR 40-90 mL/min/1.
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