Publications by authors named "F Godard"
Background And Aims: Primary lung tumors (PLTs) in children are rare, and surgery remains the key to ensure remission. Here we describe the PLTs clinical characteristics, their management, and the pulmonary outcome following surgery.
Methods: We carried out a French national cohort of pediatric PLTs from 2013 to 2023 from the FRACTURE rare pediatric tumors national database.
Article Synopsis
- A 65-year-old man with hypercalcemia due to hyperparathyroidism was sent for an 18 F-fluorocholine PET/CT to find abnormal parathyroid glands.
- The imaging unexpectedly showed a brain metastasis from a pulmonary large cell neuroendocrine carcinoma along with a parathyroid adenoma.
- This case highlights how FCH PET/CT can be useful in assessing hyperparathyroidism and can also uncover hidden cancers.
Article Synopsis
- Diffuse midline glioma, H3K27-altered, is a new subtype of diffuse astrocytoma, marked by a specific histone mutation (H3K27M).
- This rare and severe condition primarily affects children and has a particularly poor prognosis.
- The case reported involves a 30-year-old woman diagnosed with this type of glioma, highlighting its occurrence outside the typical pediatric demographic.
Article Synopsis
- The study aimed to assess if texture analysis features from pretreatment unenhanced CT images could predict clinical outcomes in patients with high-tumor-burden follicular lymphoma undergoing immunochemotherapy and rituximab maintenance.
- A total of 72 patients were included, and specific texture metrics (skewness and kurtosis) from the CT scans were evaluated in relation to progression-free survival (PFS), time to next treatment (TTNT), and overall survival.
- Results indicated that skewness and kurtosis values could serve as useful predictive biomarkers, with specific skewness thresholds linked to worse outcomes in terms of PFS and TTNT.
Patients (pts) with asymptomatic low-burden follicular lymphoma (FL) are usually observed at diagnosis. Time to lymphoma treatment (TLT) initiation can however be very heterogeneous and risk factors of progression are poorly studied. Our study evaluated 201 pts with grade 1-3a low-tumor burden FL diagnosed in four French centers between 2010 and 2020 and managed by a watch and wait strategy in real-life settings.
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