Biological evaluation and osteogenic potential of polyhydroxybutyrate-keratin/AlO electrospun nanocomposite scaffold: A novel bone regeneration construct.

In this study, the effect of alumina nanowire on the physical and biological properties of polyhydroxybutyrate-keratin (PHB-K) electrospun scaffold was investigated. First, PHB-K/alumina nanowire nanocomposite scaffolds were made with an optimal concentration of 3 wt% alumina nanowire by using the electrospinning method. The samples were examined in terms of morphology, porosity, tensile strength, contact angle, biodegradability, bioactivity, cell viability, ALP activity, mineralization ability, and gene expression.

Anti-oxidative properties of nanocrocin in Zearalenone induced toxicity on Hek293 cell; The novel formulation and cellular assessment.

Background: Zearalenone (ZEA) is a mycotoxin produced by fungi and induces cytotoxicity by the generation of reactive oxygen species. The aim of this study was to evaluate and compare the nephroprotective effects of crocin and nano-crocin against ZEA-induced toxicity in HEK293 cell line via modulation of oxidative stress and special formulation to make nano-crocin.

Method: Nano-crocin physicochemical properties, such as size, load, appearance, and drug release profile were determined.

Insulin-like growth factor 1 serum levels in different stages of gastric cancer and their association with Helicobacter pylori status.

High serum insulin-like growth factor 1 (IGF-1) and positive Helicobacter pylori (H. pylori) may increase the risk of gastric cancer (GC). We aimed to investigate IGF-1 serum levels in different stages of GC patients and their association with H.

Identification of the Requirements for the Effective Human Resource Development in the Health System.

The ultimate goal of development from the perspective of human capital development is to have a long, healthy, and creative life. This study aimed to identify the requirements for the effective human resource development in the health system. This mixed method study was performed on 20 managers of Iran's health sector in the qualitative part to reach data saturation in qualitative research.