Publications by authors named "F Gautschi"

Article Synopsis
  • Chronic lung allograft dysfunction (CLAD) negatively impacts survival for lung transplant patients, with extracorporeal photopheresis (ECP) as a potential treatment to slow its progression.
  • A study at the University Hospital Zurich analyzed 105 patients who received ECP, revealing that younger patients in the earlier stages of CLAD had the best outcomes, while those in advanced stages had significantly lower survival rates.
  • The research concluded that starting ECP treatment early, especially in patients with recurrent acute allograft dysfunction, led to improved long-term survival.
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A chest X-ray (CXR) is recommended after bronchoscopies with an increased risk of pneumothorax (PTX). However, concerns regarding radiation exposure, expenses and staff requirements exist. A lung ultrasound (LUS) is a promising alternative for the detection of PTX, though data are scarce.

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Introduction: Development of chronic lung allograft dysfunction is a limiting factor for post-lung transplant survival. We evaluated whether the dose of the immunosuppressant mycophenolate mofetil or plasma concentrations of the active metabolite mycophenolic acid affect the development of chronic lung allograft dysfunction.

Methods: In this retrospective cohort study we recruited 71 patients with a lung transplant between 2010 and 2014 which survived the first year after transplantation up to 1 July 2021.

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Maximal oxygen uptake (' ), assessed by cardiopulmonary exercise testing (CPET), is an important parameter for risk assessment in patients with pulmonary hypertension (PH). However, CPET may not be available for all PH patients. Thus, we aimed to test previously published predictive models of ' from the 6-min walk distance (6MWD) for their accuracy and to create a new model.

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Background: Acute cellular rejection (ACR) is a complication after lung transplantation (LTx). The diagnosis of ACR is based on histologic findings using transbronchial forceps biopsy (FB). However, its diagnostic accuracy is limited because of the small biopsy size and crush artifacts.

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