Publications by authors named "F Gandara"
Article Synopsis
- This research introduces three methods—merged net, clip-off chemistry, and linker reinstallation— to create and manipulate metal-organic frameworks (MOFs) effectively.
- The study first demonstrates the successful formation of unique three-merged net MOFs using a specific trimeric Sc cluster and various linkers, showcasing the creation of new edge-transitive structures.
- The authors then detail the process of transforming these three-merged MOFs into two-merged versions through clip-off chemistry, which enhances their ability to remove certain pollutants, before reverting them back to three-merged structures with new linkers.
The contamination of water by per- and polyfluorinated substances (PFAS) is a pressing global issue due to their harmful effects on health and the environment. This study explores a cationic covalent organic framework (COF), TG-PD COF, for the efficient detection and removal of perfluorooctanoic acid (PFOA) from water. Synthesized via a simple sonochemical method, TG-PD COF shows remarkable selectivity and sensitivity to PFOA, with a detection limit as low as 1.
View Article and Find Full Text PDFElectrocatalytic Water Splitting in Isoindigo-based Covalent Organic Frameworks.
Angew Chem Int Ed Engl
November 2024
Article Synopsis
- Developing a cost-effective and efficient electrocatalyst for hydrogen and oxygen evolution reactions is a significant research challenge due to its potential in energy storage and conversion.
- This study presents two types of covalent organic networks synthesized from isoindigo: a crystalline 2D framework (I-TTA COF) and an amorphous fibrous polymer (I-TG COP).
- The I-TTA COF demonstrates superior electrocatalytic performance, achieving a current density of 10 mA cm-2 with minimal overpotentials for both HER and OER while maintaining its activity after extensive testing.
Background: Antibiotic resistance is a global health concern, and its prevalence among older adults and Alzheimer's disease (AD) patients is gaining attention. Understanding the extent of antibiotic resistance in these populations is critical for designing targeted interventions.
Objective: The objective of this systematic review and meta-analysis was to determine the prevalence of antibiotic resistance in older adults and AD patients with a focus on quantitative studies in order to provide comprehensive insights into the current landscape.
This study presents the use of nanoscale covalent organic frameworks (nCOFs) conjugated with tumor-targeting peptides for the targeted therapy of triple-negative breast cancer (TNBC). While peptides have previously been used for targeted delivery, their conjugation with COFs represents an innovative approach in this field. In particular, we have developed alkyne-functionalized nCOFs chemically modified with cyclic RGD peptides (Alkyn-nCOF-cRGD).
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