Publications by authors named "F Gaita"
Article Synopsis
- The study evaluates a new technique called Delta Wave Automatic Mapping for effectively identifying ablation sites in patients with Wolff-Parkinson-White Syndrome (WPW) undergoing radiofrequency catheter ablation (RFCA).
- A total of 50 patients were analyzed, with all accessory pathways successfully ablated and a median time-to-effect of 2.0 seconds, showing no recurrences during a follow-up period of about 10 months.
- The workflow eliminates the need for manual site localization by leveraging existing algorithms, relying on specific historical electrical parameters to enhance ablation success and precision.
Article Synopsis
- Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically semaglutide, show cardiovascular benefits and may reduce the incidence of atrial fibrillation (AF) in high-risk patients.
- A meta-analysis of 10 randomized clinical trials involving 12,651 patients revealed a 42% reduction in the risk of AF with semaglutide compared to placebo during an average follow-up of 68 months.
- The study found no significant differences in AF risk reduction based on the route of administration (oral or subcutaneous), as well as no influence from baseline characteristics like diabetes status or BMI.
Background: Idiopathic ventricular fibrillation (IVF) can be associated with undetected distinct conditions such as microstructural cardiomyopathic alterations (MiCM) or Purkinje (Purk) activities with structurally normal hearts.
Objectives: This study sought to evaluate the characteristics of recurrent VF recorded on implantable defibrillator electrograms, associated with these substrates.
Methods: This was a multicenter collaboration study.
Background: The prognostic impact of catheter ablation (CA) of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) patients has not yet been satisfactorily elucidated.
Objectives: The aim of the study was to assess the impact of CA of AF on clinical outcomes in a large cohort of HCM patients.
Methods: In this retrospective multicenter study, 555 HCM patients with AF were enrolled, 140 undergoing CA and 415 receiving medical therapy.
Brugada syndrome mainly affects young subjects with structurally normal heart and can cause x syncope or sudden death due to ventricular arrhythmias, even as the first manifestation, in approximately 5-10% of cases. To date, two questions remain open: how to recognize subjects who will experience arrhythmic events and how to treat them. The guidelines suggest treating subjects with a previous history of cardiac arrest or arrhythmogenic syncope, while they are unconclusive about the management of asymptomatic patients, who represent ∼90% of Brugada patients.
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