Open-source LLMs for text annotation: a practical guide for model setting and fine-tuning.

Unlabelled: This paper studies the performance of open-source Large Language Models (LLMs) in text classification tasks typical for political science research. By examining tasks like stance, topic, and relevance classification, we aim to guide scholars in making informed decisions about their use of LLMs for text analysis and to establish a baseline performance benchmark that demonstrates the models' effectiveness. Specifically, we conduct an assessment of both zero-shot and fine-tuned LLMs across a range of text annotation tasks using news articles and tweets datasets.

Activity-Based Proteome Profiling of Serum Serine Hydrolases: Application in Pediatric Abusive Head Trauma.

Purpose: Traumatic brain injury (TBI), including pediatric abusive head trauma (AHT), is the leading cause of death and disability in children and young adults worldwide. The current understanding of trauma-induced molecular changes in the brain of human subjects with intracranial hemorrhage (ICH) remains inadequate and requires further investigation to improve the outcome and management of TBI in the clinic. Calcium-mediated damage at the site of brain injury has been shown to activate several catalytic enzymes.

People are skeptical of headlines labeled as AI-generated, even if true or human-made, because they assume full AI automation.

The rise of generative AI tools has sparked debates about the labeling of AI-generated content. Yet, the impact of such labels remains uncertain. In two preregistered online experiments among US and UK participants ( = 4,976), we show that while participants did not equate "AI-generated" with "False," labeling headlines as AI-generated lowered their perceived accuracy and participants' willingness to share them, regardless of whether the headlines were true or false, and created by humans or AI.

SMYD3: a new regulator of adipocyte precursor proliferation at the early steps of differentiation.

Background: In obesity, adipose tissue undergoes a remodeling process characterized by increased adipocyte size (hypertrophia) and number (hyperplasia). The ability to tip the balance toward the hyperplastic growth, with recruitment of new fat cells through adipogenesis, seems to be critical for a healthy adipose tissue expansion, as opposed to a hypertrophic growth that is accompanied by the development of inflammation and metabolic dysfunction. However, the molecular mechanisms underlying the fine-tuned regulation of adipose tissue expansion are far from being understood.