Publications by authors named "F G Hermoso"

Introduction: Simultaneous subcutaneous emphysema, spontaneous pneumothorax, and pneumomediastinum are complications rarely observed synchronously during an acute exacerbation of bronchial asthma. Although spontaneous pneumothorax has already been reported in asthma patients in the literature, its concurrence with subcutaneous emphysema and pneumomediastinum is extremely rare except for iatrogenic conditions.

Case Study: We describe a patient who presented to the emergency room with progressive dyspnea and chest pain.

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Article Synopsis
  • * Using a lead compound (4b), researchers synthesized a new series of analogs, with the best calpain I inhibitor found to be significantly more potent than 4b, showing an IC value of 20 nM.
  • * Compound 4b exhibited uncompetitive inhibition without causing cellular toxicity and was effective in blocking chemical-induced apoptosis in human kidney cells by preventing calpain activation.
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Our lung transplant unit began activity in October 2008. We have performed 37 lung transplants with a hospital mortality of 2.7% (n = 1).

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Aims: Hyperandrogenism, although mostly due to polygenic interactions, is monogenic for some enzymatic adrenal deficiencies. This study evaluates mono- and biallelic 21-hydroxylase deficiency (21OHD)-related hyperandrogenism in pediatric patients. Sensitizing and protective polymorphisms were investigated in carriers and cryptic forms of 21OHD.

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