Publications by authors named "F G Cicero"

Concussion resulting from athletic activities is a frequent occurrence in youth, collegiate, and professional sports. The first step in concussion treatment is usually the self-reporting of concussion symptoms by athletes. Unfortunately, over the past decade, concussion nondisclosure has remained a prominent concern in concussion identification.

View Article and Find Full Text PDF
Article Synopsis
  • Biological therapies like omalizumab can effectively treat severe allergic asthma in older patients, particularly those with asthma-COPD overlap.
  • A study involving 11 patients showed that omalizumab improved symptoms within the first year, as evidenced by better Asthma Control Test (ACT) scores and fewer exacerbations.
  • Continued treatment resulted in sustained improvements in asthma control and quality of life, indicating that omalizumab is a viable option for older patients with severe asthma.
View Article and Find Full Text PDF

Background: The anti-inflammatory properties of statins have been suggested by several researches. However, clinical trials have reported incongruous findings regarding the effect of statins on the levels of inflammatory markers other than high-sensitive C-reactive protein. Therefore, a systematic review and meta-analysis of randomized clinical trials were conducted to illuminate the effect of statins on serum levels of TNF-α, MCP-1, VCAM1, and IL-6 in patients with cardiovascular diseases (CVDs).

View Article and Find Full Text PDF

Disciplines establish and enforce professional codes of ethics in order to guide ethical and safe practice. Unfortunately, ethical breaches still occur. Interestingly, it is found that breaches are often perpetrated by professionals who are aware of their codes of ethics and believe that they engage in ethical practice.

View Article and Find Full Text PDF

The choice between adaptive and preorganized architectures, or of the most effective hydrogen bonding groups to be selected, are dilemmas that supramolecular chemists must address in designing synthetic receptors for such a challenging guest as carbohydrates. In this paper, structurally related architectures featuring two alternative hydrogen bonding motifs were compared to ascertain the structural and functional origin of their binding differences and the advantages that can be expected in monosaccharide recognition. A set of structurally related macrocyclic receptors were prepared, and their binding properties were measured by NMR and ITC techniques in chloroform vs a common saccharidic target, namely, the β-octyl glycoside of D-glucose.

View Article and Find Full Text PDF