Publications by authors named "F G Carrozzo"
Article Synopsis
- Organogenesis in the uterus occurs under low oxygen levels, but preterm birth exposes infants to high oxygen, which can harm organ development and lead to conditions like necrotizing enterocolitis.
- The study investigates the role of the β3-adrenoreceptor (β3-AR) in protecting the ileum from damage caused by high oxygen levels in newborn rat pups, using a selective β3-AR agonist, BRL37344.
- Results show that a 3 mg/kg dose of BRL37344 mitigates some harmful changes caused by hyperoxia, highlighting its potential as a therapeutic approach for addressing complications related to premature birth and excessive oxygen exposure.
Article Synopsis
- Oxygen levels play a crucial role in organ development, and changes in these levels after birth can significantly affect organs like the intestine that don’t fully mature in the womb.
- This study investigates the β3-adrenoreceptor (β3-AR) agonist BRL37344 in a neonatal rat model exposed to high oxygen levels, finding that hyperoxia negatively impacts colon development by reducing certain cell types and mucin production.
- Administering a specific dose of BRL37344 (3 mg/kg) helped prevent some of these negative effects, suggesting potential therapeutic benefits for conditions resulting from too much oxygen exposure in premature infants.
Martian CO Ice Observation at High Spectral Resolution With ExoMars/TGO NOMAD.
J Geophys Res Planets
May 2022
The Nadir and Occultation for MArs Discovery (NOMAD) instrument suite aboard ExoMars/Trace Gas Orbiter spacecraft is mainly conceived for the study of minor atmospheric species, but it also offers the opportunity to investigate surface composition and aerosols properties. We investigate the information content of the Limb, Nadir, and Occultation (LNO) infrared channel of NOMAD and demonstrate how spectral orders 169, 189, and 190 can be exploited to detect surface CO ice. We study the strong CO ice absorption band at 2.
View Article and Find Full Text PDFThis work describes the correction method applied to the dataset acquired at the asteroid (4) Vesta by the visible channel of the visible and infrared mapping spectrometer. The rising detector temperature during data acquisitions in the visible wavelengths leads to a spectral slope increase over the whole spectral range. This limits the accuracy of the studies of the Vesta surface in this wavelength range.
View Article and Find Full Text PDFData acquired at Ceres by the visible channel of the Visible and InfraRed mapping spectrometer (VIR) on board the NASA Dawn spacecraft are affected by the temperatures of both the visible (VIS) and the infrared (IR) sensors, which are, respectively, a charged coupled device and a HgCdTe array. The variations of the visible channel temperatures measured during the sessions of acquisitions are correlated with the variations in the spectral slope and shape for all the mission phases. The IR channel temperature is more stable during the acquisitions; nonetheless, it is characterized by a bimodal distribution whether the cryocooler (and, therefore, the IR channel) is used or not during the visible channel operations.
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