Publications by authors named "F Fucilli"
Long-Term Outcomes of Balloon TACE for HCC: An European Multicentre Single-Arm Retrospective Study.
Cardiovasc Intervent Radiol
August 2024
Purpose: To report response rates (using mRECIST), overall survival (OS), progression-free survival and local tumour recurrence-free survival (LRFS) of balloon-occluded transarterial chemoembolisation (bTACE) for hepatocellular carcinoma (HCC).
Materials And Methods: Patients from five European centres treated with conventional or drug-eluting microsphere bTACE for HCC were included, and patients already lost to follow-up before 12 months were excluded. Possible factors contributing to LRFS and OS were evaluated with Cox proportional hazards models.
Article Synopsis
- The study focused on the impact of a Low Glycemic Index Mediterranean Diet (LGIMD) combined with exercise on individuals with Non-Alcoholic Fatty Liver Disease (NAFLD) and Type 2 Diabetes (T2D) over one year.
- Participants included 58 subjects aged 18-65, who experienced significant improvements in their glycosylated hemoglobin (HbA1c) levels, especially those with moderate and severe NAFLD.
- The findings suggest that lifestyle changes through diet and exercise can positively affect glucose metabolism and help manage the symptoms of both NAFLD and T2D.
Article Synopsis
- The study looked at how a low glycemic index Mediterranean diet (LGIMD) combined with exercise (CEP) affects metabolic-associated fatty liver disease (MAFLD).
- 54 participants were monitored over 12 months, and results showed that adherence to the diet and exercise significantly influenced body mass index (BMI) and insulin resistance indicators.
- The findings indicate that LGIMD/CEP not only improved MAFLD outcomes but also suggested that BMI and insulin resistance are strong predictors of recovery from the disease.
Introduction: The aim of this multicenter comparison of balloon-occluded transarterial chemoembolization (B-TACE) versus conventional TACE (cTACE) in treating hepatocellular carcinoma (HCC) was to assess in which size range the 2 techniques offered higher complete response (CR) and objective response (OR) rates in a single session, and to evaluate the possibility of using B-TACE to reduce the need for re-treatment.
Methods: 325 patients were retrospectively evaluated: 91 patients in the B-TACE group (22 with cTACE [B-cTACE] and 69 with drug-eluting microsphere TACE [B-DEM-TACE]) and 234 in the cTACE group. The results were compared according to tumor size: (A) <30 mm, (B) 30-50 mm, and (C) >50 mm; OR and CR rates after the first session and the number of TACE re-interventions within a 6-month period were also evaluated using propensity score matching (PSM).
Purpose: The aim of this retrospective multicentric study was to compare the tumour response rates of Balloon-occluded Transarterial Chemoembolisation (B-TACE) to non-B-TACE using propensity score matching (PSM) in patients with hepatocellular carcinoma and to investigate the clinical benefit, such as lower rates of TACE re-intervention achieved using B-TACE.
Material And Methods: The B-TACE procedures (n = 96 patients) were compared with a control group of non-B-TACE treatments (n = 434 pts), performed with conventional (cTACE) or drug-eluting microspheres TACE (DEM-TACE). Data were collected from six European centres from 2015 to 2019.